Validation of a simplified-geometry model of inhaled formoterol pharmacodynamics in asthmatic patients

PharmacoKinetics (PK) and PharmacoDynamics (PD) mathematical models of inhaled bronchodilators represent useful tools for understanding the mechanisms of drug action and for the individuation of therapy regimens. A PK/PD model for inhaled bronchoactive compounds was previously proposed, incorporatin...

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Bibliographic Details
Main Authors: Simona Panunzi, Claudio Gaz, Fabio Cibella, Andrea De Gaetano
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2022.1018050/full