MiR-2113 overexpression attenuates sepsis-induced acute pulmonary dysfunction, inflammation and fibrosis by inhibition of HMGB1

MiR-2113 overexpression attenuates sepsis-induced acute pulmonary dysfunction, inflammation and fibrosis by inhibition of HMGB1

Purpose: Sepsis-induced acute lung injury is related to high mortality. MiR-2113 possesses important functions in human diseases. This research aimed to clarify the role and mechanism of miR-2113 in sepsis-induced acute lung injury. Methods: The expression of miR-2113 in lipopolysaccharide (LPS)-ind...

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Bibliographic Details
Main Authors: Yong Li, Hui-Ling Xu, Xiu-Wen Kang, Suo Xu, Zhi-Fang Mou
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Heliyon
Subjects:
MiR-2113
Sepsis
Acute pulmonary dysfunction
Inflammation
fibrosis
High-mobility group box 1
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023099802

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http://www.sciencedirect.com/science/article/pii/S2405844023099802

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