Efficacy decrease of antiviral agents when administered to ongoing hepatitis C virus infections in cell culture

Efficacy decrease of antiviral agents when administered to ongoing hepatitis C virus infections in cell culture

We report a quantification of the decrease of effectiveness of antiviral agents directed to hepatitis C virus, when the agents are added during an ongoing infection in cell culture vs. when they are added at the beginning of the infection. Major determinants of the decrease of inhibitory activity ar...

Full description

Bibliographic Details
Main Authors: Carlos García-Crespo, Lucía Vázquez-Sirvent, Pilar Somovilla, María Eugenia Soria, Isabel Gallego, Ana Isabel de Ávila, Brenda Martínez-González, Antoni Durán-Pastor, Esteban Domingo, Celia Perales
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Microbiology
Subjects:
daclatasvir
sofosbuvir
favipiravir
ribavirin
direct acting antivirals
viral fitness
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.960676/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2022.960676/full

Similar Items