Variations in the Frequencies of Polymorphisms in the CYP450s Genes in Eight Major Ethnicities of Iran: A Review of the Human Data

Variations in the Frequencies of Polymorphisms in the CYP450s Genes in Eight Major Ethnicities of Iran: A Review of the Human Data

Genetic polymorphisms in cytochrome P450 genes can cause variation in metabolism. Thus, single nucleotide variants significantly impact drug pharmacokinetics, toxicity factors, and efficacy and safety of medicines. The distribution of CYP450 alleles varies drastically across ethnicities, with signif...

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Bibliographic Details
Main Authors: Navid Neyshaburinezhad, Hengameh Ghasim, Mohammadreza Rouini, Youssef Daali, Yalda H. Ardakani
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Journal of Personalized Medicine
Subjects:
Iranian ethnicities
CYP450 genotype
polymorphism
SNP
Online Access:https://www.mdpi.com/2075-4426/12/11/1848

Internet

https://www.mdpi.com/2075-4426/12/11/1848

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