A Platform of Patient-Derived Microtumors Identifies Individual Treatment Responses and Therapeutic Vulnerabilities in Ovarian Cancer

A Platform of Patient-Derived Microtumors Identifies Individual Treatment Responses and Therapeutic Vulnerabilities in Ovarian Cancer

In light of the frequent development of therapeutic resistance in cancer treatment, there is a strong need for personalized model systems representing patient tumor heterogeneity, while enabling parallel drug testing and identification of appropriate treatment responses in individual patients. Using...

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Bibliographic Details
Main Authors: Nicole Anderle, André Koch, Berthold Gierke, Anna-Lena Keller, Annette Staebler, Andreas Hartkopf, Sara Y. Brucker, Michael Pawlak, Katja Schenke-Layland, Christian Schmees
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Cancers
Subjects:
patient-derived tumor model
ovarian cancer
anti-cancer drug sensitivity
RPPA protein profiling
cancer immunotherapy
Online Access:https://www.mdpi.com/2072-6694/14/12/2895

Internet

https://www.mdpi.com/2072-6694/14/12/2895

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