Bcl-xL Is Spontaneously Inserted into Preassembled Nanodiscs and Stimulates Bax Insertion in a Cell-Free Protein Synthesis System

The antiapoptotic protein Bcl-xL is a major regulator of cell death and survival, but many aspects of its functions remain elusive. It is mostly localized in the mitochondrial outer membrane (MOM) owing to its C-terminal hydrophobic α-helix. In order to gain further information about its membrane or...

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Bibliographic Details
Main Authors: Akandé Rouchidane Eyitayo, Axel Boudier-Lemosquet, Stéphane Chaignepain, Muriel Priault, Stéphen Manon
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/13/6/876