Combination of Dexamethasone and Tofacitinib Reduces Xenogeneic MSC-Induced Immune Responses in a Mouse Model of Alzheimer’s Disease

Combination of Dexamethasone and Tofacitinib Reduces Xenogeneic MSC-Induced Immune Responses in a Mouse Model of Alzheimer’s Disease

We have recently reported on how transplantation of human mesenchymal stem cells (MSCs) into the mouse parenchyma generated immune responses. To facilitate the clinical translation of MSC-based AD therapy, the safety and efficacy of human derived MSCs (hMSCs) must be confirmed in the pre-clinical st...

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Bibliographic Details
Main Authors: Na Kyung Lee, Su Hyeon Myeong, Jung Won Hwang, Jason K. Sa, Hyo Jin Son, Hee Jin Kim, Hyemin Jang, Jong Wook Chang, Duk L. Na
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Biomedicines
Subjects:
immunosuppressant
Alzheimer’s disease
dexamethasone
tofacitinib
immune response
Online Access:https://www.mdpi.com/2227-9059/10/8/1882

Internet

https://www.mdpi.com/2227-9059/10/8/1882

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