Sequestration of free cholesterol in cell membranes by prions correlates with cytoplasmic phospholipase A<sub>2 </sub>activation

<p>Abstract</p> <p>Background</p> <p>The transmissible spongiform encephalopathies (TSEs), otherwise known as the prion diseases, occur following the conversion of the normal cellular prion protein (PrP<sup>C</sup>) to an alternatively folded isoform (PrP<...

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Bibliographic Details
Main Authors: Williams Alun, Tayebi Mourad, Bate Clive
Format: Article
Language:English
Published: BMC 2008-02-01
Series:BMC Biology
Online Access:http://www.biomedcentral.com/1741-7007/6/8