Hydrophobic Alpha-Helical Short Peptides in Overlapping Reading Frames of the Coronavirus Genome

Hydrophobic Alpha-Helical Short Peptides in Overlapping Reading Frames of the Coronavirus Genome

In this study, we show that the coronavirus (CoV) genome may encode many functional hydrophobic alpha-helical peptides (HAHPs) in overlapping reading frames of major coronaviral proteins throughout the entire viral genome. These HAHPs can theoretically be expressed from non-canonical sub-genomic (sg...

Full description

Bibliographic Details
Main Authors: Takashi Okura, Kazuya Shirato, Masatoshi Kakizaki, Satoko Sugimoto, Shutoku Matsuyama, Tomohisa Tanaka, Yohei Kume, Mina Chishiki, Takashi Ono, Kohji Moriishi, Masashi Sonoyama, Mitsuaki Hosoya, Koichi Hashimoto, Katsumi Maenaka, Makoto Takeda
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Pathogens
Subjects:
coronavirus
SARS-CoV-2
overlapping frame
sub-genomic RNA
nidovirus
alpha-helix
Online Access:https://www.mdpi.com/2076-0817/11/8/877

Internet

https://www.mdpi.com/2076-0817/11/8/877

Similar Items