The immune checkpoint LAG-3 is expressed by melanoma cells and correlates with clinical progression of the melanoma

The immune checkpoint LAG-3 is expressed by melanoma cells and correlates with clinical progression of the melanoma

Immune checkpoint blockers have substantially improved prognosis of melanoma patients, nevertheless, resistance remains a significant problem. Here, intrinsic and extrinsic factors in the tumor microenvironment are discussed, including the expression of alternative immune checkpoints such as lymphoc...

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Bibliographic Details
Main Authors: Melanie Wiecken, Devayani Machiraju, Shounak Chakraborty, Eva-Maria Mayr, Bénédicte Lenoir, Rosa Eurich, Jasmin Richter, Nicole Pfarr, Niels Halama, Jessica C. Hassel
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:OncoImmunology
Subjects:
Immune checkpoints
LAG-3
melanoma
TIM-3
Online Access:https://www.tandfonline.com/doi/10.1080/2162402X.2024.2430066

Internet

https://www.tandfonline.com/doi/10.1080/2162402X.2024.2430066

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