Noninvasive detection of pancreatic ductal adenocarcinoma using the methylation signature of circulating tumour DNA

Noninvasive detection of pancreatic ductal adenocarcinoma using the methylation signature of circulating tumour DNA

Abstract Background Pancreatic ductal adenocarcinoma (PDAC) has the lowest overall survival rate primarily due to the late onset of symptoms and rapid progression. Reliable and accurate tests for early detection are lacking. We aimed to develop a noninvasive test for early PDAC detection by capturin...

Full description

Bibliographic Details
Main Authors: Huanwen Wu, Shiwei Guo, Xiaoding Liu, Yatong Li, Zhixi Su, Qiye He, Xiaoqian Liu, Zhiwen Zhang, Lianyuan Yu, Xiaohan Shi, Suizhi Gao, Huan Wang, Yaqi Pan, Chengcheng Ma, Rui Liu, Menghua Dai, Gang Jin, Zhiyong Liang
Format: Article
Language:English
Published: BMC 2022-11-01
Series:BMC Medicine
Subjects:
PDAC
Early detection
Circulating tumour DNA methylation
Methylation haplotype blocks
Online Access:https://doi.org/10.1186/s12916-022-02647-z

Internet

https://doi.org/10.1186/s12916-022-02647-z

Similar Items