Nanoparticle vaccines based on the receptor binding domain of porcine deltacoronavirus elicit robust protective immune responses in mice

Nanoparticle vaccines based on the receptor binding domain of porcine deltacoronavirus elicit robust protective immune responses in mice

BackgroundPorcine deltacoronavirus (PDCoV), a novel swine enteropathogenic coronavirus, challenges the global swine industry. Currently, there are no approaches preventing swine from PDCoV infection.MethodsA new PDCoV strain named JS2211 was isolated. Next, the dimer receptor binding domain of PDCoV...

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Bibliographic Details
Main Authors: Yuanhong Wang, Junhan Song, Xiaoying Deng, Junna Wang, Miao Zhang, Yun Liu, Pan Tang, Huili Liu, Yanjun Zhou, Guangzhi Tong, Guoxin Li, Lingxue Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Immunology
Subjects:
porcine deltacoronavirus
nanoparticle vaccine
ferritin
SpyTag/SpyCatcher
RBD
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1328266/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2024.1328266/full

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