Nanoparticle vaccines based on the receptor binding domain of porcine deltacoronavirus elicit robust protective immune responses in mice

Nanoparticle vaccines based on the receptor binding domain of porcine deltacoronavirus elicit robust protective immune responses in mice

BackgroundPorcine deltacoronavirus (PDCoV), a novel swine enteropathogenic coronavirus, challenges the global swine industry. Currently, there are no approaches preventing swine from PDCoV infection.MethodsA new PDCoV strain named JS2211 was isolated. Next, the dimer receptor binding domain of PDCoV...

Full description

Bibliographic Details
Main Authors:	Yuanhong Wang, Junhan Song, Xiaoying Deng, Junna Wang, Miao Zhang, Yun Liu, Pan Tang, Huili Liu, Yanjun Zhou, Guangzhi Tong, Guoxin Li, Lingxue Yu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-03-01
Series:	Frontiers in Immunology
Subjects:	porcine deltacoronavirus nanoparticle vaccine ferritin SpyTag/SpyCatcher RBD
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1328266/full

Similar Items

A modular and self-adjuvanted multivalent vaccine platform based on porcine circovirus virus-like nanoparticles
by: Ze-Hui Liu, et al.
Published: (2022-11-01)

Modulating the Viscoelastic Properties of Covalently Crosslinked Protein Hydrogels
by: Rossana Boni, et al.
Published: (2023-06-01)

Cellular synthesis of protein pretzelanes
by: Xilin Bai, et al.
Published: (2022-06-01)

Neutralizing Efficacy of Encapsulin Nanoparticles against SARS-CoV2 Variants of Concern
by: Sara Khaleeq, et al.
Published: (2023-01-01)

Fiber manipulation and post-assembly nanobody conjugation for adenoviral vector retargeting through SpyTag-SpyCatcher protein ligation
by: Maryam Kadkhodazadeh, et al.
Published: (2022-12-01)

A nanoparticle vaccine displaying the ookinete PSOP25 antigen elicits transmission-blocking antibody response against Plasmodium berghei
by: Guixiang Yao, et al.
Published: (2023-11-01)

SpyDisplay: A versatile phage display selection system using SpyTag/SpyCatcher technology
by: Sarah-Jane Kellmann, et al.
Published: (2023-12-01)

Isopeptide Bonding <i>In Planta</i> Allows Functionalization of Elongated Flexuous Proteinaceous Viral Nanoparticles, including Non-Viable Constructs by Other Means
by: Daniel A. Truchado, et al.
Published: (2023-01-01)

Nimotuzumab Site-Specifically Labeled with <sup>89</sup>Zr and <sup>225</sup>Ac Using SpyTag/SpyCatcher for PET Imaging and Alpha Particle Radioimmunotherapy of Epidermal Growth Factor Receptor Positive Cancers
by: Viswas Raja Solomon, et al.
Published: (2020-11-01)

A novel synthetic trivalent single chain variable fragment (tri-scFv) construction platform based on the SpyTag/SpyCatcher protein ligase system
by: Md. Kausar Alam, et al.
Published: (2018-09-01)

Analysis of Engineered Tobacco Mosaic Virus and Potato Virus X Nanoparticles as Carriers for Biocatalysts
by: Juliane Schuphan, et al.
Published: (2021-08-01)

A Plant-Produced Virus-Like Particle Displaying Envelope Protein Domain III Elicits an Immune Response Against West Nile Virus in Mice
by: Jennifer Stander, et al.
Published: (2021-09-01)

Protein scaffolds: A tool for multi-enzyme assembly
by: Shubhada Gad, et al.
Published: (2021-12-01)

Tagging and catching: rapid isolation and efficient labeling of organelles using the covalent Spy-System in planta
by: Martina Lang, et al.
Published: (2020-09-01)

A bacterial outer membrane vesicle-based click vaccine elicits potent immune response against Staphylococcus aureus in mice
by: Jingjing Sun, et al.
Published: (2023-01-01)

A preparation strategy for protein-oriented immobilized silica magnetic beads with Spy chemistry for ligand fishing
by: Yu Yi, et al.
Published: (2022-06-01)

Programmable Polyproteams of Tyrosine Ammonia Lyases as Cross-Linked Enzymes for Synthesizing <i>p</i>-Coumaric Acid
by: Mingyu Jia, et al.
Published: (2022-07-01)

Modular vaccine platform based on the norovirus-like particle
by: Vili Lampinen, et al.
Published: (2021-01-01)

Construction of Bi-Enzyme Self-Assembly Clusters Based on SpyCatcher/SpyTag for the Efficient Biosynthesis of (R)-Ethyl 2-hydroxy-4-phenylbutyrate
by: Jinmei Wang, et al.
Published: (2023-01-01)

Multi-Enzyme Assembly on T4 Phage Scaffold
by: Jinny L. Liu, et al.
Published: (2020-06-01)

Biological Applications of Synthetic Binders Isolated from a Conceptually New Adhiron Library
by: Claudia D’Ercole, et al.
Published: (2023-10-01)

SpyTag/SpyCatcher display of influenza M2e peptide on norovirus-like particle provides stronger immunization than direct genetic fusion
by: Vili Lampinen, et al.
Published: (2023-06-01)

Cross‐species transmission of deltacoronavirus and the origin of porcine deltacoronavirus
by: Xu Ye, et al.
Published: (2020-10-01)

Development of a Versatile Method to Construct Direct Electron Transfer-Type Enzyme Complexes Employing SpyCatcher/SpyTag System
by: Takumi Yanase, et al.
Published: (2023-01-01)

Display of multiple proteins on engineered canine parvovirus-like particles expressed in cultured silkworm cells and silkworm larvae
by: Jian Xu, et al.
Published: (2023-02-01)

Efficient Preparation of High-Purity Fucoxanthinol by SpyTag-Tailored Active Cholesterol Esterase Aggregates
by: Wenhui Jin, et al.
Published: (2022-11-01)

Identifying Cleaved and Noncleaved Targets of Small Interfering RNAs and MicroRNAs in Mammalian Cells by SpyCLIP
by: Yao Zhang, et al.
Published: (2020-12-01)

Emergence of a Novel Genotype of Pigeon Deltacoronavirus Closely Related to Porcine Deltacoronavirus HKU15 and Sparrow Deltacoronavirus HKU17 in a Live Poultry Market in Shandong Province, China
by: Guo-Lin Wang, et al.
Published: (2023-08-01)

Porcine Deltacoronavirus, Thailand, 2015
by: Taveesak Janetanakit, et al.
Published: (2016-04-01)

Inhibition of porcine deltacoronavirus entry and replication by Cepharanthine
by: Yumei Sun, et al.
Published: (2024-02-01)

Nicotinamide Efficiently Suppresses Porcine Epidemic Diarrhea Virus and Porcine Deltacoronavirus Replication
by: Mingxia Li, et al.
Published: (2023-07-01)

A cVLP-Based Vaccine Displaying Full-Length PCSK9 Elicits a Higher Reduction in Plasma PCSK9 Than Similar Peptide-Based cVLP Vaccines
by: Louise Goksøyr, et al.
Published: (2022-12-01)

Porcine Deltacoronavirus in Mainland China
by: Nan Dong, et al.
Published: (2015-12-01)

Characterization and Pathogenicity of the Porcine Deltacoronavirus Isolated in Southwest China
by: Yujia Zhao, et al.
Published: (2019-11-01)

Genetic Characterization and Evolution of Porcine Deltacoronavirus Isolated in the Republic of Korea in 2022
by: Hye-Ryung Kim, et al.
Published: (2023-05-01)

Antiviral Effect of Selenomethionine on Porcine Deltacoronavirus in Pig Kidney Epithelial Cells
by: Zhihua Ren, et al.
Published: (2022-02-01)

A simple and rapid identification method for newly emerged porcine Deltacoronavirus with loop-mediated isothermal amplification
by: Fanfan Zhang, et al.
Published: (2017-09-01)

Construction, Characterization and Application of Recombinant Porcine Deltacoronavirus Expressing Nanoluciferase
by: Puxian Fang, et al.
Published: (2021-10-01)

Identification of a Monoclonal Antibody against Porcine Deltacoronavirus Membrane Protein
by: Huiguang Wu, et al.
Published: (2023-09-01)

Porcine Deltacoronaviruses: Origin, Evolution, Cross-Species Transmission and Zoonotic Potential
by: Fanzhi Kong, et al.
Published: (2022-01-01)