Hepatic Proteomic Analysis of Selenoprotein T Knockout Mice by TMT: Implications for the Role of Selenoprotein T in Glucose and Lipid Metabolism

Hepatic Proteomic Analysis of Selenoprotein T Knockout Mice by TMT: Implications for the Role of Selenoprotein T in Glucose and Lipid Metabolism

Selenoprotein T (SELENOT, SelT), a thioredoxin-like enzyme, exerts an essential oxidoreductase activity in the endoplasmic reticulum. However, its precise function remains unknown. To gain more understanding of SELENOT function, a conventional global <i>Selenot</i> knockout (KO) mouse mo...

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Bibliographic Details
Main Authors: Ke Li, Tiejun Feng, Leyan Liu, Hongmei Liu, Kaixun Huang, Jun Zhou
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
selenium
selenoprotein T
knockout
diabetes
glucose and lipid metabolism
proteomics
Online Access:https://www.mdpi.com/1422-0067/22/16/8515

Internet

https://www.mdpi.com/1422-0067/22/16/8515

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