Design and Engineering of Deimmunized Vaccinia Viral Vectors
Vaccinia viral (VV) vectors are increasingly used in oncolytic virus therapy and vaccine development for cancer and infectious diseases. However, their effectiveness is hindered by the strong anti-viral immune response induced by the viral vector. In this review, we discuss the strategies to deimmun...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-11-01
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Series: | Biomedicines |
Subjects: | |
Online Access: | https://www.mdpi.com/2227-9059/8/11/491 |