Enhanced antibody-antigen structure prediction from molecular docking using AlphaFold2

Abstract Predicting the structure of antibody-antigen complexes has tremendous value in biomedical research but unfortunately suffers from a poor performance in real-life applications. AlphaFold2 (AF2) has provided renewed hope for improvements in the field of protein–protein docking but has shown l...

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Bibliographic Details
Main Authors: Francis Gaudreault, Christopher R. Corbeil, Traian Sulea
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-42090-5