Chronic inflammation deters natural killer cell fitness and cytotoxicity in myeloid leukemia

Chronic inflammation deters natural killer cell fitness and cytotoxicity in myeloid leukemia

Abstract: Natural killer (NK) cells play an integral role in immunosurveillance against myeloid malignancies, with their mature phenotype and abundance linked to prolonged treatment-free remission in chronic myeloid leukemia (CML). However, NK cell function is suppressed during the disease, and the...

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Bibliographic Details
Main Authors: Valeriya Kuznetsova, Vaidehi Krishnan, Amanda Costa, Xi Ren, Tiffany D. Ricketts, Sweta B. Patel, Ashley N. Connelly, Paran Goel, Joshua P. Knapp, Alana M. Franceski, Francesca Luca, Lorena Lobo de Figueiredo-Pontes, Ravi Bhatia, Shyam Prabhakar, S. Tiong Ong, Robert S. Welner
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Blood Advances
Online Access:http://www.sciencedirect.com/science/article/pii/S2473952924006694

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http://www.sciencedirect.com/science/article/pii/S2473952924006694

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