Progressive Hemorrhage and Myotoxicity Induced by Echis carinatus Venom in Murine Model: Neutralization by Inhibitor Cocktail of N,N,N',N'-Tetrakis (2-Pyridylmethyl) Ethane-1,2-Diamine and Silymarin.

Progressive Hemorrhage and Myotoxicity Induced by Echis carinatus Venom in Murine Model: Neutralization by Inhibitor Cocktail of N,N,N',N'-Tetrakis (2-Pyridylmethyl) Ethane-1,2-Diamine and Silymarin.

Viperbite is often associated with severe local toxicity, including progressive hemorrhage and myotoxicity, persistent even after the administration of anti-snake venom (ASV). In the recent past, investigations have revealed the orchestrated actions of Zn2+ metalloproteases (Zn2+MPs), phospholipase...

Full description

Bibliographic Details
Main Authors: Ankanahalli N Nanjaraj Urs, Chandrasekaran Ramakrishnan, Vikram Joshi, Kanve Nagaraj Suvilesh, Teregowda Veerabasappa Gowda, Devadasan Velmurugan, Bannikuppe Sannanaik Vishwanath
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4537139?pdf=render

Internet

http://europepmc.org/articles/PMC4537139?pdf=render

Similar Items