Acteoside alleviates UUO-induced inflammation and fibrosis by regulating the HMGN1/TLR4/TREM1 signaling pathway

Purpose Acteoside (Act), a phenylethanoid compound that was first isolated from mullein, has been widely used for the investigation of anti-inflammatory and anti-fibrotic effect. However, the mechanism of Act against unilateral ureteral obstruction (UUO)-mediated renal injury is largely unknown. The...

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Bibliographic Details
Main Authors: Yan Mao, Jiali Yu, Jingjing Da, Fuxun Yu, Yan Zha
Format: Article
Language:English
Published: PeerJ Inc. 2023-01-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/14765.pdf