Tiliroside Attenuates NLRP3 Inflammasome Activation in Macrophages and Protects against Acute Lung Injury in Mice

Tiliroside Attenuates NLRP3 Inflammasome Activation in Macrophages and Protects against Acute Lung Injury in Mice

The Nod-like receptor family PYRIN domain containing 3 (NLRP3) inflammasome is a multiprotein signaling complex that plays a pivotal role in innate immunity, and the dysregulated NLRP3 inflammasome activation is implicated in various diseases. Tiliroside is a natural flavonoid in multiple medicinal...

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Bibliographic Details
Main Authors: Chao Zhong, Jing Yang, Keke Deng, Xiaoya Lang, Jiangtao Zhang, Min Li, Liang Qiu, Guoyue Zhong, Jun Yu
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Molecules
Subjects:
tiliroside
NLRP3 inflammasome
macrophages
AMPK
mitochondrial damage
acute lung injury
Online Access:https://www.mdpi.com/1420-3049/28/22/7527

Internet

https://www.mdpi.com/1420-3049/28/22/7527

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