Negative costimulatory molecule B7-H4 mediates protective effect of mesenchymal stem cells on experimental autoimmune encephalomyelitis

Negative costimulatory molecule B7-H4 mediates protective effect of mesenchymal stem cells on experimental autoimmune encephalomyelitis

Our previous study has shown that the negative co-stimulatory molecule B7-H4 is constitutively expressed on human bone marrow-derived mesenchymal stem cells (MSCs) and mediates their immunomodulatory effect on T cells in vitro. However, whether B7-H4 on MSCs can be responsible for their immunomodula...

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Bibliographic Details
Main Authors: Xiao-Pei Ji, Yan-Zheng Gu, Hao Li, Zhou Yin, Nagam Varshithreddy, Ling-Tao Tang, Nan Li, Ying Zhang, Ming-Yuan Wang, Qin Shi, Si-Wei You, Xi-Ying Luan, Wan-Li Dong, Qi Fang, Xue-Guang Zhang, Qun Xue
Format: Article
Language:English
Published: Aristotle University of Thessaloniki 2022-12-01
Series:Journal of Biological Research - Thessaloniki
Subjects:
b7-h4
mesenchymal stem cell
experimental autoimmune encephalomyelitis
immunomodulation
Online Access:https://ejournals.lib.auth.gr/jbiolres/article/view/8647

Internet

https://ejournals.lib.auth.gr/jbiolres/article/view/8647

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