Lymphocyte-Specific Protein 1 Regulates Expression and Stability of Endothelial Nitric Oxide Synthase

Lymphocyte-Specific Protein 1 Regulates Expression and Stability of Endothelial Nitric Oxide Synthase

Nitric oxide (NO), synthesized by endothelial nitric oxide synthase (eNOS), plays a critical role in blood pressure regulation. Genome-wide association studies have identified genetic susceptibility loci for hypertension in human lymphocyte-specific protein 1 (LSP1) gene. LSP1 is recognized as modul...

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Bibliographic Details
Main Authors: Musstafa Smeir, Paulos Chumala, George S. Katselis, Lixin Liu
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Biomolecules
Subjects:
endothelial cells
eNOS
LSP1
CRISPR-Cas9 gene editing
adenovirus overexpression
mass spectrometry
Online Access:https://www.mdpi.com/2218-273X/14/1/111

Internet

https://www.mdpi.com/2218-273X/14/1/111

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