MICA+ Tumor Cell Upregulated Macrophage-Secreted MMP9 via PROS1-AXL Axis to Induce Tumor Immune Escape in Advanced Hepatocellular Carcinoma (HCC)

MICA+ Tumor Cell Upregulated Macrophage-Secreted MMP9 via PROS1-AXL Axis to Induce Tumor Immune Escape in Advanced Hepatocellular Carcinoma (HCC)

Background: tumor-associated macrophages (TAMs) constitute a significant proportion of non-cancerous cells within the intricate tumor microenvironment (TME) of hepatocellular carcinoma (HCC). Understanding the communication between macrophages and tumor cells, as well as investigating potential sign...

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Bibliographic Details
Main Authors: Qiulin Wu, Xicai Li, Yan Yang, Jingquan Huang, Ming Yao, Jianjun Li, Yubin Huang, Xiaoyong Cai, David A. Geller, Yihe Yan
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Cancers
Subjects:
HCC
MICA
PROS1
AXL
MMP9
macrophage
Online Access:https://www.mdpi.com/2072-6694/16/2/269

Internet

https://www.mdpi.com/2072-6694/16/2/269

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