Transcription initiation activity sets replication origin efficiency in mammalian cells.
Genomic mapping of DNA replication origins (ORIs) in mammals provides a powerful means for understanding the regulatory complexity of our genome. Here we combine a genome-wide approach to identify preferential sites of DNA replication initiation at 0.4% of the mouse genome with detailed molecular an...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2009-04-01
|
| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC2661365?pdf=render |