Transcription initiation activity sets replication origin efficiency in mammalian cells.
Genomic mapping of DNA replication origins (ORIs) in mammals provides a powerful means for understanding the regulatory complexity of our genome. Here we combine a genome-wide approach to identify preferential sites of DNA replication initiation at 0.4% of the mouse genome with detailed molecular an...
Main Authors: | Joana Sequeira-Mendes, Ramón Díaz-Uriarte, Anwyn Apedaile, Derek Huntley, Neil Brockdorff, María Gómez |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-04-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC2661365?pdf=render |
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