Reversible suppression of cyclooxygenase 2 (COX-2) expression in vivo by inducible RNA interference.

Reversible suppression of cyclooxygenase 2 (COX-2) expression in vivo by inducible RNA interference.

Prostaglandin-endoperoxide synthase 2 (PTGS2), also known as cyclooxygenase 2 (COX-2), plays a critical role in many normal physiological functions and modulates a variety of pathological conditions. The ability to turn endogenous COX-2 on and off in a reversible fashion, at specific times and in sp...

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Bibliographic Details
Main Authors: Anne K Zaiss, Johannes Zuber, Chun Chu, Hidevaldo B Machado, Jing Jiao, Arthur B Catapang, Tomo-o Ishikawa, Jose S Gil, Scott W Lowe, Harvey R Herschman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4079684?pdf=render

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http://europepmc.org/articles/PMC4079684?pdf=render

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