Synapse type-specific proteomic dissection identifies IgSF8 as a hippocampal CA3 microcircuit organizer
Mossy fiber synapses are key in CA3 microcircuit function. Here, the authors profile the mossy fiber synapse proteome and cell-surface interactome. They uncover a diverse repertoire of cell-surface proteins and identify the receptor IgSF8 as a regulator of CA3 microcircuit connectivity and function.
| Main Authors: | , , , , , , , , , , , , , |
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| 格式: | 文件 |
| 语言: | English |
| 出版: |
Nature Portfolio
2020-10-01
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| 丛编: | Nature Communications |
| 在线阅读: | https://doi.org/10.1038/s41467-020-18956-x |