Muscle Pathology in Dystrophic Rats and Zebrafish Is Unresponsive to Taurine Treatment, Compared to the <i>mdx</i> Mouse Model for Duchenne Muscular Dystrophy

Muscle Pathology in Dystrophic Rats and Zebrafish Is Unresponsive to Taurine Treatment, Compared to the <i>mdx</i> Mouse Model for Duchenne Muscular Dystrophy

Inflammation and oxidative stress are strongly implicated in the pathology of Duchenne muscular dystrophy (DMD), and the sulphur-containing amino acid taurine ameliorates both and decreases dystropathology in the <i>mdx</i> mouse model for DMD. We therefore further tested taurine as a th...

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Bibliographic Details
Main Authors: Jessica R. Terrill, Corinne Huchet, Caroline Le Guiner, Aude Lafoux, Dorian Caudal, Ankita Tulangekar, Robert J. Bryson-Richardson, Tamar E. Sztal, Miranda D. Grounds, Peter G. Arthur
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Metabolites
Subjects:
duchenne muscular dystrophy
DMD<sup>mdx</sup> rat
<i>dmd</i> zebrafish
taurine
therapies for DMD
animal models for DMD
Online Access:https://www.mdpi.com/2218-1989/13/2/232

Internet

https://www.mdpi.com/2218-1989/13/2/232

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