RintC: fast and accuracy-aware decomposition of distributions of RNA secondary structures with extended logsumexp

RintC: fast and accuracy-aware decomposition of distributions of RNA secondary structures with extended logsumexp

Abstract Background Analysis of secondary structures is essential for understanding the functions of RNAs. Because RNA molecules thermally fluctuate, it is necessary to analyze the probability distributions of their secondary structures. Existing methods, however, are not applicable to long RNAs owi...

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Bibliographic Details
Main Authors: Hiroki Takizawa, Junichi Iwakiri, Kiyoshi Asai
Format: Article
Language:English
Published: BMC 2020-05-01
Series:BMC Bioinformatics
Subjects:
RNA secondary structure
Dynamic programming
Accuracy-guaranteed numerical computation
Interval arithmetic
Ribosomal RNA.
Online Access:http://link.springer.com/article/10.1186/s12859-020-3535-5

Internet

http://link.springer.com/article/10.1186/s12859-020-3535-5

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