Evaluating the effects of vitamin D Level on airway obstruction in two asthma endotypes in humans and in two mouse models with different intake of vitamin D during early-life

Evaluating the effects of vitamin D Level on airway obstruction in two asthma endotypes in humans and in two mouse models with different intake of vitamin D during early-life

IntroductionAsthma is primarily divided into two categories: type 2 (T2-high) and non-type 2 (T2-low). A relationship between asthma severity and vitamin D deficiency has been identified, but its impact on each asthma endotype remains unknown.MethodsWe clinically examined the influence of vitamin D...

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Bibliographic Details
Main Authors: Yan Zhou, Yali Qiu, Wuping Bao, Lei Han, Yishu Xue, Yingying Zhang, Xue Tian, Qiang Fu, Chengjian Lv, Dongning Yin, Min Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Immunology
Subjects:
vitamin D
airway inflammation
airway resistance
asthma endotypes
T2-low asthma
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1107031/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1107031/full

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