4492 The role of creatine in developmental myelination and remyelination

OBJECTIVES/GOALS: Oligodendrocytes (OL) are glial cells of the central nervous system (CNS) responsible for the energy demanding task of generating myelin sheaths during development and remyelination after demyelinating injury. One metabolite shown to significantly increase ATP production in OL is t...

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Bibliographic Details
Main Authors: Lauren Rosko, Victoria N Smith, Jeffrey K. Huang
Format: Article
Language:English
Published: Cambridge University Press 2020-06-01
Series:Journal of Clinical and Translational Science
Online Access:https://www.cambridge.org/core/product/identifier/S2059866120003180/type/journal_article