Stem-Like Cells in Bone Sarcomas: Implications for Tumorigenesis

Stem-Like Cells in Bone Sarcomas: Implications for Tumorigenesis

Bone sarcomas are a clinically and molecularly heterogeneous group of malignancies characterized by varying degrees of mesenchymal differentiation. Despite advances in medical and surgical management, survival rates for high-grade tumors have remained static at 50% to 70%. Tumor stem cells have been...

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Bibliographic Details
Main Authors: C. Parker Gibbs, Valery G. Kukekov, John D. Reith, Olga Tchigrinova, Oleg N. Suslov, Edward W. Scott, Steven C. Ghivizzani, Tatyana N. Ignatova, Dennis A. Steindler
Format: Article
Language:English
Published: Elsevier 2005-11-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Sarcoma
Stro-1
self-renewal
pluripotent Oct 3/4, Nanog
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558605800314

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http://www.sciencedirect.com/science/article/pii/S1476558605800314

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