Development and Characterisation of a Four-Plex Assay to Measure <i>Streptococcus pyogenes</i> Antigen-Specific IgG in Human Sera

The measurement of antibodies to vaccine antigens is crucial for research towards a safe and effective vaccine for <i>Streptococcus pyogenes</i> (Strep A). We describe the establishment and detailed characterisation of a four-plex assay to measure IgG to the Strep A vaccine antigens SpyC...

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Bibliographic Details
Main Authors: Alexander J. Keeley, Martina Carducci, Luisa Massai, Mariagrazia Pizza, Thushan I. de Silva, Danilo G. Moriel, Omar Rossi
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Methods and Protocols
Subjects:
Online Access:https://www.mdpi.com/2409-9279/5/4/55