Combined adipose-derived mesenchymal stem cell and antibiotic therapy can effectively treat periprosthetic joint infection in rats

Combined adipose-derived mesenchymal stem cell and antibiotic therapy can effectively treat periprosthetic joint infection in rats

Abstract Periprosthetic joint infection (PJI) is characterized by biofilm infection, which is difficult to alleviate while preserving implant integrity. Furthermore, long-term antibiotic therapy may increase the prevalence of drug-resistant bacterial strains, necessitating a non-antibacterial approa...

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Bibliographic Details
Main Authors: Yuki Yamamuro, Tamon Kabata, Takayuki Nojima, Katsuhiro Hayashi, Masaharu Tokoro, Yoshitomo Kajino, Daisuke Inoue, Takaaki Ohmori, Junya Yoshitani, Takuro Ueno, Ken Ueoka, Atsushi Taninaka, Tomoyuki Kataoka, Yoshitomo Saiki, Yu Yanagi, Hiroyuki Tsuchiya
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-30087-z

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https://doi.org/10.1038/s41598-023-30087-z

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