Anion exchange HPLC monitoring of mRNA in vitro transcription reactions to support mRNA manufacturing process development

mRNA technology has recently demonstrated the ability to significantly change the timeline for developing and delivering a new vaccine from years to months. The potential of mRNA technology for rapid vaccine development has recently been highlighted by the successful development and approval of two...

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Bibliographic Details
Main Authors: Emma N. Welbourne, Kate A. Loveday, Adithya Nair, Ehsan Nourafkan, Jixin Qu, Ken Cook, Zoltán Kis, Mark J. Dickman
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Molecular Biosciences
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2024.1250833/full