Pathway-Centric Integrative Analysis Identifies RRM2 as a Prognostic Marker in Breast Cancer Associated with Poor Survival and Tamoxifen Resistance

Pathway-Centric Integrative Analysis Identifies RRM2 as a Prognostic Marker in Breast Cancer Associated with Poor Survival and Tamoxifen Resistance

Breast cancer (BCa) molecular subtypes include luminal A, luminal B, normal-like, HER-2–enriched, and basal-like tumors, among which luminal B and basal-like cancers are highly aggressive. Biochemical pathways associated with patient survival or treatment response in these more aggressive subtypes a...

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Bibliographic Details
Main Authors: Nagireddy Putluri, Suman Maity, Ramakrishna Kommagani, Chad J. Creighton, Vasanta Putluri, Fengju Chen, Sarmishta Nanda, Salil Kumar Bhowmik, Atsushi Terunuma, Tiffany Dorsey, Agostina Nardone, Xiaoyong Fu, Chad Shaw, Tapasree Roy Sarkar, Rachel Schiff, John P. Lydon, Bert W. O’Malley, Stefan Ambs, Gokul M. Das, George Michailidis, Arun Sreekumar
Format: Article
Language:English
Published: Elsevier 2014-05-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S147655861400061X

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http://www.sciencedirect.com/science/article/pii/S147655861400061X

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