Cyclic RGD functionalized PLGA nanoparticles loaded with noncovalent complex of indocyanine green with urokinase for synergistic thrombolysis

Cyclic RGD functionalized PLGA nanoparticles loaded with noncovalent complex of indocyanine green with urokinase for synergistic thrombolysis

Thrombotic diseases have the characteristics of long latency period, rapid onset, and high mortality rate, which seriously threaten people’s life and health. The aim of this research is to fabricate a novel indocyanine green complex of urokinase (ICG@uPA) and employ the amphiphilic PEG-PLGA polymer...

Full description

Bibliographic Details
Main Authors: Sha Zhang, Jinjie Li, Jiefeng Ren, Zaiyao Xue, Xinlian Qi, Quanjin Si
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
phototherapy
PLGA nanoparticles
thrombus
plasminogen activators
targeted delivery
activated platelet
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.945531/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2022.945531/full

Similar Items