Detection of gene mutations and gene–gene fusions in circulating cell‐free DNA of glioblastoma patients: an avenue for clinically relevant diagnostic analysis

Detection of gene mutations and gene–gene fusions in circulating cell‐free DNA of glioblastoma patients: an avenue for clinically relevant diagnostic analysis

Glioblastoma (GBM) is the most common type of glioma and is uniformly fatal. Currently, tumour heterogeneity and mutation acquisition are major impedances for tailoring personalized therapy. We collected blood and tumour tissue samples from 25 GBM patients and 25 blood samples from healthy controls....

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Bibliographic Details
Main Authors: Vikrant Palande, Tali Siegal, Rajesh Detroja, Alessandro Gorohovski, Rainer Glass, Charlotte Flueh, Andrew A. Kanner, Yoseph Laviv, Sagi Har‐Nof, Adva Levy‐Barda, Marcela Viviana Karpuj, Marina Kurtz, Shira Perez, Dorith Raviv Shay, Milana Frenkel‐Morgenstern
Format: Article
Language:English
Published: Wiley 2022-05-01
Series:Molecular Oncology
Subjects:
circulating cell‐free DNA
druggable
gene mutation
gene‐gene fusion
glioblastoma
liquid biopsy
Online Access:https://doi.org/10.1002/1878-0261.13157

Internet

https://doi.org/10.1002/1878-0261.13157

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