Single-cell transcriptional signature-based drug repurposing and in vitro evaluation in colorectal cancer

Abstract Background The need for intelligent and effective treatment of diseases and the increase in drug design costs have raised drug repurposing as one of the effective strategies in biomedicine. There are various computational methods for drug repurposing, one of which is using transcription sig...

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Bibliographic Details
Main Authors: Roohallah Mahdi-Esferizi, Zahra Shiasi, Razieh Heidari, Ali Najafi, Issa Mahmoudi, Fatemeh Elahian, Shahram Tahmasebian
Format: Article
Language:English
Published: BMC 2024-03-01
Series:BMC Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12885-024-12142-8