mRNA-Based Anti-TCR CDR3 Tumour Vaccine for T-Cell Lymphoma

mRNA-Based Anti-TCR CDR3 Tumour Vaccine for T-Cell Lymphoma

Efficient vaccination can be achieved by injections of in vitro transcribed mRNA (ivt mRNA) coding for antigens. This vaccine format is particularly versatile and allows the production of individualised vaccines conferring, T-cell immunity against specific cancer mutations. The CDR3 hypervariable re...

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Bibliographic Details
Main Authors: Marina Tusup, Severin Läuchli, Natalia Teresa Jarzebska, Lars E. French, Yun-Tsan Chang, Maya Vonow-Eisenring, Andreas Su, Thomas M. Kündig, Emmanuella Guenova, Steve Pascolo
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Pharmaceutics
Subjects:
in vitro transcribed mRNA
ivt mRNA
vaccine
T-cell lymphoma
CTCL
TCR
Online Access:https://www.mdpi.com/1999-4923/13/7/1040

Internet

https://www.mdpi.com/1999-4923/13/7/1040

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