Upf2-Mediated Nonsense-Mediated Degradation Pathway Involved in Genetic Compensation of <i>TrpA1</i> Knockout Mutant Silkworm (<i>Bombyx mori</i>)

Upf2-Mediated Nonsense-Mediated Degradation Pathway Involved in Genetic Compensation of <i>TrpA1</i> Knockout Mutant Silkworm (<i>Bombyx mori</i>)

Genetic mutations leading to premature termination codons are known to have detrimental effects. Using the Lepidoptera model insect, the silkworm (<i>Bombyx mori</i>), we explored the genetic compensatory response triggered by mutations with premature termination codons. Additionally, we...

Full description

Bibliographic Details
Main Authors: Dong-Yue Wang, Juan Zhu, Yi-Zhong Zhang, Qian-Yi Cui, Shan-Shan Wang, Yang-Wei Ning, Xing-Jia Shen
Format: Article
Language:English
Published: MDPI AG 2024-04-01
Series:Insects
Subjects:
<i>BmTrpA1</i>
CRISPR/Cas9
<i>Bombyx mori</i>
genetic compensation response
nonsense-mediated mRNA degradation pathway
Online Access:https://www.mdpi.com/2075-4450/15/5/313

Internet

https://www.mdpi.com/2075-4450/15/5/313

Similar Items