Airway regulatory T cells are decreased in COPD with a rapid decline in lung function

Airway regulatory T cells are decreased in COPD with a rapid decline in lung function

Abstract Background Differences in the expression of regulatory T cells (Tregs) have been suggested to explain why some smokers develop COPD and some do not. Upregulation of Tregs in response to smoking would restrain airway inflammation and thus the development of COPD; while the absense of such up...

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Bibliographic Details
Main Authors: Jonas Eriksson Ström, Jamshid Pourazar, Robert Linder, Anders Blomberg, Anne Lindberg, Anders Bucht, Annelie F. Behndig
Format: Article
Language:English
Published: BMC 2020-12-01
Series:Respiratory Research
Subjects:
Chronic obstructive pulmonary disease
Disease mechanisms
Lung function decline
Smoking habits
Bronchoalveolar lavage
Regulatory T cells
Online Access:https://doi.org/10.1186/s12931-020-01593-9

Internet

https://doi.org/10.1186/s12931-020-01593-9

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