Effects of angiotensin II blockade on cardiomyocyte regeneration after myocardial infarction in rats

Introduction: We studied the effects of angiotensin type 1 receptor blockade (ARB) on formation of new cardiomyocytes, neovascularization and ventricular remodelling after myocardial infarction (MI). Methods: Male Wistar rats with MI or sham-operated controls were treated with either losartan or veh...

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Bibliographic Details
Main Authors: Heli Segersvärd, Päivi Lakkisto, Hanna Forsten, Katariina Immonen, Riikka Kosonen, Eeva Palojoki, Esko Kankuri, Ari Harjula, Mika Laine, Ilkka Tikkanen
Format: Article
Language:English
Published: SAGE Publications 2015-03-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.1177/1470320313487567