Regulatory Mechanisms and Reversal of CD8<sup>+</sup>T Cell Exhaustion: A Literature Review
CD8<sup>+</sup>T cell exhaustion is a state of T cell dysfunction during chronic infection and tumor progression. Exhausted CD8<sup>+</sup>T cells are characterized by low effector function, high expression of inhibitory receptors, unique metabolic patterns, and altered trans...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-04-01
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| Series: | Biology |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2079-7737/12/4/541 |