Host-Derived Leukotriene B4 Is Critical for Resistance against Invasive Pulmonary Aspergillosis

Host-Derived Leukotriene B4 Is Critical for Resistance against Invasive Pulmonary Aspergillosis

Aspergillus fumigatus is a mold that causes severe pulmonary infections. Our knowledge of how immune competent hosts maintain control of fungal infections while constantly being exposed to fungi is rapidly emerging. It is known that timely neutrophil recruitment to and activation in the lungs is cri...

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Bibliographic Details
Main Authors: Alayna K. Caffrey-Carr, Kimberly M. Hilmer, Caitlin H. Kowalski, Kelly M. Shepardson, Rachel M. Temple, Robert A. Cramer, Joshua J. Obar
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Immunology
Subjects:
Aspergillus fumigatus
leukotrienes
leukotriene B4
neutrophils
eosinophils
hypoxia inducible factor-1α
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01984/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01984/full

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