Investigation of the Factors Responsible for the Poor Oral Bioavailability of Acacetin in Rats: Physicochemical and Biopharmaceutical Aspects

Investigation of the Factors Responsible for the Poor Oral Bioavailability of Acacetin in Rats: Physicochemical and Biopharmaceutical Aspects

Acacetin, an important ingredient of acacia honey and a component of several medicinal plants, exhibits therapeutic effects such as antioxidative, anticancer, anti-inflammatory, and anti-plasmodial activities. However, to date, studies reporting a systematic investigation of the in vivo fate of oral...

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Bibliographic Details
Main Authors: Dong-Gyun Han, Eunju Cha, Jeongmin Joo, Ji Sun Hwang, Sanghyun Kim, Taeuk Park, Yoo-Seong Jeong, Han-Joo Maeng, Sang-Bum Kim, In-Soo Yoon
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Pharmaceutics
Subjects:
acacetin
solubility
stability
gastrointestinal absorption
tissue metabolism
bioavailability
Online Access:https://www.mdpi.com/1999-4923/13/2/175

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https://www.mdpi.com/1999-4923/13/2/175

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