Phenotypic characterization of spatial immune infiltration niches in non-small cell lung cancer

Phenotypic characterization of spatial immune infiltration niches in non-small cell lung cancer

ABSTRACTThe immune microenvironment of non-small cell lung cancer (NSCLC) is heterogeneous, which impedes the prediction of response to immune checkpoint inhibitors. We have mapped the expression of 49 proteins to spatial immune niches in 33 NSCLC tumors and report key differences in phenotype and f...

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Bibliographic Details
Main Authors: Anna Sandström Gerdtsson, Mattis Knulst, Johan Botling, Artur Mezheyeuski, Patrick Micke, Sara Ek
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:OncoImmunology
Subjects:
NSCLC
immune infiltration
tertiary lymphoid structures
tumor-infiltrating leukocytes
spatial omics
Online Access:https://www.tandfonline.com/doi/10.1080/2162402X.2023.2206725

Internet

https://www.tandfonline.com/doi/10.1080/2162402X.2023.2206725

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