Adhesion rings surround invadopodia and promote maturation

Summary Invasion and metastasis are aggressive cancer phenotypes that are highly related to the ability of cancer cells to degrade extracellular matrix (ECM). At the cellular level, specialized actin-rich structures called invadopodia mediate focal matrix degradation by serving as exocytic sites for...

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Bibliographic Details
Main Authors: Kevin M. Branch, Daisuke Hoshino, Alissa M. Weaver
Format: Article
Language:English
Published: The Company of Biologists 2012-06-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/1/8/711