Adhesion rings surround invadopodia and promote maturation
Summary Invasion and metastasis are aggressive cancer phenotypes that are highly related to the ability of cancer cells to degrade extracellular matrix (ECM). At the cellular level, specialized actin-rich structures called invadopodia mediate focal matrix degradation by serving as exocytic sites for...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2012-06-01
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Series: | Biology Open |
Subjects: | |
Online Access: | http://bio.biologists.org/content/1/8/711 |