Random allelic expression in the adult human body

Summary: Genes are typically assumed to express both parental alleles similarly, yet cell lines show random allelic expression (RAE) for many autosomal genes that could shape genetic effects. Thus, understanding RAE in human tissues could improve our understanding of phenotypic variation. Here, we d...

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Bibliographic Details
Main Authors: Stephanie N. Kravitz, Elliott Ferris, Michael I. Love, Alun Thomas, Aaron R. Quinlan, Christopher Gregg
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124722018460