Synthetic Notch-Receptor-Mediated Transmission of a Transient Signal into Permanent Information via CRISPR/Cas9-Based Genome Editing

Synthetic receptor biology and genome editing are emerging techniques, both of which are currently beginning to be used in preclinical and clinical applications. We were interested in whether a combination of these techniques approaches would allow for the generation of a novel type of reporter cell...

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Bibliographic Details
Main Authors: Malte Sgodda, Susanne Alfken, Axel Schambach, Reto Eggenschwiler, Pawel Fidzinski, Michael Hummel, Tobias Cantz
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/9/9/1929